IBX5980432E7F390 Doctors Describe “Concrete Therapeutic Near” for Mesothelioma - Health Cancer

Doctors Describe “Concrete Therapeutic Near” for Mesothelioma

Doctors Describe “Concrete Therapeutic Near” for Mesothelioma

A team of medical researchers in Italy have accomplishd what they are calling “excellent” tumor control and survival results in malignant pleural mesothelioma patients utune a combination of surgery, chemotherapy, and radiotherapy.





Caused by expocertain to asbestos, mesothelioma typically spreads fastly across the lung-encatune membrane called the pleura. There is no telln cure but treatments are improving. In the current prospective learn, 20 malignant pleural mesothelioma patients underwent radical pleurectomy/decortication followed by high doses of radiation.



After surgeons removed as much of the visible mesothelioma tumor and surrounding tissue as possible, patients received 50Gy of radiation to the effected middle of their chest, delivered in 25 frbehaveions. Regions of particular concern for mesothelioma regrowth got an extra radiation “boost” to 60Gy. Nineteen of the patients also received chemotherapy with a combination of cisplatin and pemetrexed.



When the researchers calculated how well mesothelioma tumors were controlled by the multi-modal treatment near and how long patients survived, the results were encouraging. The median overall survival was 33 months. The Kaplan-Meier analysis tool was used to estifriend that 70% of mesothelioma patients would still be alive at 2 years and almost half (49%) would still be living at 3 years. Given that the majority of mesothelioma patients die within a year of diagnosis, the learn’s survival results are impressive.



“High dose radiation therapy following radical pleurectomy/decortication led to excellent loco-regional control and survival results in malignant pleural mesothelioma patients,” the researchers report in the diary Lung Clevercer. They go on to say that the overall survival swifts utune this combination of surgery, chemotherapy, and high-dose radiation are “among the best observed in recent studies.”



While seven patients did eventually develop metastatic mesothelioma (clevercer growth in another area), only three patients had regrowth at the site of the original mesothelioma tumor. The Italian researchers concluded that the learn results suggest a “concrete therapeutic near” for mesothelioma, an aggressive clevercer for which there are few viable treatment options.



Source:



Minatel, E, et al, “Radical pleurectomy/decortication followed by high dose of radiation therapy for malignant pleural mesothelioma. Final results with long-term follow-up”, October 27, 2013, Lung Clevercer, Epub ahead of print.



http://www.survivingmesothelioma.com/news/view.asp?ID=001553#.U0wn_qiSySo



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